Looping around Reprogramming: The Topological Memory of Induced Pluripotency.

Gonzales, Kevin Andrew Uy; Ng, Huck-Hui

Gonzales, Kevin Andrew Uy; Ng, Huck-Hui.

Afiliación

Gonzales KA; Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672.
Ng HH; Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672; Department of Biochemistry, National University of Singapore, Singapore 117597; Department of Biological Sciences, National University of Singapore, Singapore 117597; School of Biological Sciences, Nanyang Technological University, Singapore 639798. Electronic address: nghh@gis.a-star.edu.sg.

Cell Stem Cell ; 18(5): 557-9, 2016 05 05.

Article en En | MEDLINE | ID: mdl-27152435

ABSTRACT

ABSTRACT

Genome architecture is associated with cellular identity, but how this organization changes during reprogramming is not well understood. Now in Cell Stem Cell, Krijger et al. (2016) and Beagan et al. (2016) report 3D chromatin interaction maps before and after reprogramming, providing evidence for topological memory in induced pluripotent stem cells.

Asunto(s)

Reprogramación Celular; Células Madre Pluripotentes Inducidas; Cromatina; Genoma; Humanos

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Reprogramación Celular / Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: Cell Stem Cell Año: 2016 Tipo del documento: Article

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