solarius: an R interface to SOLAR for variance component analysis in pedigrees.
Bioinformatics
; 32(12): 1901-2, 2016 06 15.
Article
en En
| MEDLINE
| ID: mdl-27153684
ABSTRACT
UNLABELLED The open source environment R is one of the most widely used software for statistical computing. It provides a variety of applications including statistical genetics. Most of the powerful tools for quantitative genetic analyses are stand-alone free programs developed by researchers in academia. SOLAR is one of the standard software programs to perform linkage and association mappings of the quantitative trait loci (QTLs) in pedigrees of arbitrary size and complexity. solarius allows the user to exploit the variance component methods implemented in SOLAR. It automates such routine operations as formatting pedigree and phenotype data. It parses also the model output and contains summary and plotting functions for exploration of the results. In addition, solarius enables parallel computing of the linkage and association analyses that makes the calculation of genome-wide scans more efficient. AVAILABILITY AND IMPLEMENTATION solarius is available on CRAN and on GitHub https//github.com/ugcd/solarius CONTACT aziyatdinov@santpau.cat.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Programas Informáticos
/
Sitios de Carácter Cuantitativo
/
Ligamiento Genético
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2016
Tipo del documento:
Article
País de afiliación:
España