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Effects of theta-rhythm transcranial alternating current stimulation (4.5 Hz-tACS) in patients with clozapine-resistant negative symptoms of schizophrenia: a case series.
Kallel, Lassaad; Mondino, Marine; Brunelin, Jerome.
Afiliación
  • Kallel L; Résidence ENNESRINE, Cab G12, 2036, La Soukra, Tunisia.
  • Mondino M; Centre Interdisciplinaire de Recherche en Réadaptation et en Intégration Sociale, Centre de Recherche de l'Institut Universitaire en Santé Mentale, Medical School, Université Laval, Québec, QC, Canada.
  • Brunelin J; Centre Interdisciplinaire de Recherche en Réadaptation et en Intégration Sociale, Centre de Recherche de l'Institut Universitaire en Santé Mentale, Medical School, Université Laval, Québec, QC, Canada. jerome.brunelin@ch-le-vinatier.fr.
J Neural Transm (Vienna) ; 123(10): 1213-7, 2016 10.
Article en En | MEDLINE | ID: mdl-27194229
ABSTRACT
Our aim was to assess the efficacy and safety of theta-rhythm transcranial Alternating Current Stimulation (4.5 Hz-tACS) in patients with clozapine-resistant symptoms of schizophrenia. In an open case series, 3 patients received 20 sessions of 4.5 Hz-tACS (20 min, 2 mA) applied over the dorsolateral prefrontal cortex. The patients exhibited a decrease of negative symptoms (-10 %), general symptoms (-18 %) and an improvement of insight into the illness (-25 %). 4.5 Hz-tACS might be a suitable alternative treatment for clozapine-resistant symptoms of schizophrenia.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esquizofrenia / Ritmo Teta / Corteza Prefrontal / Estimulación Transcraneal de Corriente Directa Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: J Neural Transm (Vienna) Año: 2016 Tipo del documento: Article País de afiliación: Túnez

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esquizofrenia / Ritmo Teta / Corteza Prefrontal / Estimulación Transcraneal de Corriente Directa Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: J Neural Transm (Vienna) Año: 2016 Tipo del documento: Article País de afiliación: Túnez