1400W, a highly selective inducible nitric oxide synthase inhibitor is a potential disease modifier in the rat kainate model of temporal lobe epilepsy.

Puttachary, Sreekanth; Sharma, Shaunik; Verma, Saurabh; Yang, Yang; Putra, Marson; Thippeswamy, Achala; Luo, Diou; Thippeswamy, Thimmasettappa

Puttachary, Sreekanth; Sharma, Shaunik; Verma, Saurabh; Yang, Yang; Putra, Marson; Thippeswamy, Achala; Luo, Diou; Thippeswamy, Thimmasettappa.

Afiliación

Puttachary S; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.
Sharma S; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.
Verma S; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.
Yang Y; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.
Putra M; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.
Thippeswamy A; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.
Luo D; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.
Thippeswamy T; Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA.

Neurobiol Dis ; 93: 184-200, 2016 09.

Article en En | MEDLINE | ID: mdl-27208748

Asunto(s)

Amidinas/farmacología; Bencilaminas/farmacología; Epilepsia del Lóbulo Temporal/tratamiento farmacológico; Hipocampo/efectos de los fármacos; Óxido Nítrico Sintasa de Tipo II/antagonistas & inhibidores; Estado Epiléptico/tratamiento farmacológico; Animales; Modelos Animales de Enfermedad; Epilepsia del Lóbulo Temporal/inducido químicamente; Epilepsia del Lóbulo Temporal/metabolismo; Masculino; Neuronas/efectos de los fármacos; Ratas Sprague-Dawley; Estado Epiléptico/inducido químicamente

Palabras clave

Bloodbrain barrier; GLT-1; K(ir) 4.1; Long-term continuous video-EEG; Mossy fiber sprouting; Multi-electrode array; Neurodegeneration; Neuroinflammation; Serum albumin; Spontaneous recurrent seizures

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Estado Epiléptico / Bencilaminas / Epilepsia del Lóbulo Temporal / Óxido Nítrico Sintasa de Tipo II / Amidinas / Hipocampo Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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