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Platelets contribute to amyloid-ß aggregation in cerebral vessels through integrin αIIbß3-induced outside-in signaling and clusterin release.
Donner, Lili; Fälker, Knut; Gremer, Lothar; Klinker, Stefan; Pagani, Giulia; Ljungberg, Liza U; Lothmann, Kimberley; Rizzi, Federica; Schaller, Martin; Gohlke, Holger; Willbold, Dieter; Grenegard, Magnus; Elvers, Margitta.
Afiliación
  • Donner L; Department of Clinical and Experimental Hemostasis, Hemotherapy and Transfusion Medicine, Heinrich Heine University, 40225 Düsseldorf, Germany.
  • Fälker K; Cardiovascular Research Centre, Örebro University, SE-701 82 Örebro, Sweden.
  • Gremer L; Institute of Physical Biology, Heinrich Heine University, 40225 Düsseldorf, Germany. Institute of Structural Biochemistry (ICS-6), Research Centre Jülich, 52425 Jülich, Germany.
  • Klinker S; Institute of Physical Biology, Heinrich Heine University, 40225 Düsseldorf, Germany.
  • Pagani G; Institute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University, 40225 Düsseldorf, Germany.
  • Ljungberg LU; Cardiovascular Research Centre, Örebro University, SE-701 82 Örebro, Sweden.
  • Lothmann K; Institute of Physical Biology, Heinrich Heine University, 40225 Düsseldorf, Germany.
  • Rizzi F; Department of Biomedical, Biotechnological, and Translation Sciences, University of Parma, Via Volturno 39/a, 43126 Parma, Italy. Centre for Molecular and Translational Oncology (COMT), University of Parma, Parco Area delle Scienze 11/a, 43124 Parma, Italy. National Institute of Biostructure and Bio
  • Schaller M; Department of Dermatology, University of Tübingen, 72076 Tübingen, Germany.
  • Gohlke H; Institute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University, 40225 Düsseldorf, Germany.
  • Willbold D; Institute of Physical Biology, Heinrich Heine University, 40225 Düsseldorf, Germany. Institute of Structural Biochemistry (ICS-6), Research Centre Jülich, 52425 Jülich, Germany.
  • Grenegard M; Cardiovascular Research Centre, Örebro University, SE-701 82 Örebro, Sweden.
  • Elvers M; Department of Clinical and Experimental Hemostasis, Hemotherapy and Transfusion Medicine, Heinrich Heine University, 40225 Düsseldorf, Germany. margitta.elvers@med.uni-duesseldorf.de.
Sci Signal ; 9(429): ra52, 2016 05 24.
Article en En | MEDLINE | ID: mdl-27221710
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plaquetas / Integrinas / Péptidos beta-Amiloides / Clusterina Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plaquetas / Integrinas / Péptidos beta-Amiloides / Clusterina Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania