Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B.

Villarroel-Campos, David; Henríquez, Daniel R; Bodaleo, Felipe J; Oguchi, Mai E; Bronfman, Francisca C; Fukuda, Mitsunori; Gonzalez-Billault, Christian

Villarroel-Campos, David; Henríquez, Daniel R; Bodaleo, Felipe J; Oguchi, Mai E; Bronfman, Francisca C; Fukuda, Mitsunori; Gonzalez-Billault, Christian.

Afiliación

Villarroel-Campos D; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile, Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
Henríquez DR; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile.
Bodaleo FJ; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile, Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
Oguchi ME; Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Tohoku University, Sendai 980-8577, Japan.
Bronfman FC; MINREB and CARE Center, Department of Physiology, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile, and.
Fukuda M; Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Tohoku University, Sendai 980-8577, Japan.
Gonzalez-Billault C; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile, Center for Geroscience, Brain Health and Metabolism, Santiago, Chile, The Buck Institute for Research on Aging, Novato, California 94945, chrgonza@uchile.cl.

J Neurosci ; 36(27): 7298-313, 2016 07 06.

Article en En | MEDLINE | ID: mdl-27383602

Asunto(s)

Axones/fisiología; Proteínas Asociadas a Microtúbulos/metabolismo; Neuronas/citología; Proteínas Serina-Treonina Quinasas/metabolismo; Proteínas de Unión al GTP rab/metabolismo; Animales; Línea Celular Transformada; Células Cultivadas; Chlorocebus aethiops; Embrión de Mamíferos; Regulación de la Expresión Génica/genética; Hipocampo/citología; Ratones; Ratones Transgénicos; Mutación/genética; Proteínas del Tejido Nervioso/metabolismo; Oligodesoxirribonucleótidos Antisentido/farmacología; Proteínas Serina-Treonina Quinasas/genética; Proteolisis/efectos de los fármacos; ARN Interferente Pequeño/farmacología; Ratas; Proteína de Unión al GTP cdc42/metabolismo; Proteínas de Unión al GTP rab/genética

Palabras clave

MAP1B; Rab35; axon development; p53-related protein kinase; ubiquitin proteosome

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Axones / Proteínas Serina-Treonina Quinasas / Proteínas de Unión al GTP rab / Proteínas Asociadas a Microtúbulos / Neuronas Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: J Neurosci Año: 2016 Tipo del documento: Article País de afiliación: Chile

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