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Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.
Ito, Genta; Katsemonova, Kristina; Tonelli, Francesca; Lis, Pawel; Baptista, Marco A S; Shpiro, Natalia; Duddy, Graham; Wilson, Steve; Ho, Philip Wing-Lok; Ho, Shu-Leong; Reith, Alastair D; Alessi, Dario R.
Afiliación
  • Ito G; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K. genta-ito@umin.ac.jp d.r.alessi@dundee.ac.uk.
  • Katsemonova K; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Tonelli F; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Lis P; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Baptista MA; The Michael J. Fox Foundation for Parkinson's Research, Grand Central Station, P.O. Box 4777, New York, NY 10163, U.S.A.
  • Shpiro N; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Duddy G; Molecular Discovery Research, GlaxoSmithKline Pharmaceuticals R&D, New Frontiers Science Park, Harlow, Essex CM19 5AD, U.K.
  • Wilson S; RD Platform Technology & Science, GlaxoSmithKline, U.K.
  • Ho PW; Division of Neurology, Department of Medicine, University of Hong Kong, Hong Kong.
  • Ho SL; Division of Neurology, Department of Medicine, University of Hong Kong, Hong Kong.
  • Reith AD; Neurodegeneration Discovery Performance Unit, RD Neurosciences, GlaxoSmithKline Pharmaceuticals R&D, Stevenage, U.K.
  • Alessi DR; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K. genta-ito@umin.ac.jp d.r.alessi@dundee.ac.uk.
Biochem J ; 473(17): 2671-85, 2016 09 01.
Article en En | MEDLINE | ID: mdl-27474410
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas / Proteínas de Unión al GTP rab / Inhibidores de Proteínas Quinasas / Proteína 2 Quinasa Serina-Treonina Rica en Repeticiones de Leucina Límite: Animals Idioma: En Revista: Biochem J Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas / Proteínas de Unión al GTP rab / Inhibidores de Proteínas Quinasas / Proteína 2 Quinasa Serina-Treonina Rica en Repeticiones de Leucina Límite: Animals Idioma: En Revista: Biochem J Año: 2016 Tipo del documento: Article