Respiratory Muscle Assessment in Acute Guillain-Barré Syndrome.
Lung
; 194(5): 821-8, 2016 10.
Article
en En
| MEDLINE
| ID: mdl-27506902
ABSTRACT
PURPOSE:
Guillain-Barré Syndrome (GBS) is a life-threatening disease due to respiratory muscle involvement. This study aimed at objectively assessing the course of respiratory muscle function in GBS subjects within the first week of admission to an intensive care unit.METHODS:
Medical Research Council Sum Score (MRC-SS), vigorimetry, spirometry, and respiratory muscle function tests (inspiratory/expiratory muscle strength PImax/PEmax, sniff nasal pressure SnPna) were assessed twice daily. GBS Disability Score (GBS-DS) was assessed once daily. On days one (d1) and seven (d7), blood gases and twitch mouth pressure during magnetic phrenic nerve stimulation (Pmo,tw) were additionally evaluated.RESULTS:
Nine subjects were included. MRC-SS, vigorimetry, PImax, and SnPna increased between d1 and d7. GBS-DS, spirometry and Pmo,tw remained unaltered. Only SnPna correlated closely with the MRC-SS on both d1 (r = 0.77, p = 0.02) and d7 (r = 0.74, p = 0.02).CONCLUSION:
SnPna was the only parameter that correlated with MRC-SS, while the current gold standard of spirometry measurement did not.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Músculos Respiratorios
/
Síndrome de Guillain-Barré
/
Fuerza Muscular
Límite:
Aged
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Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Lung
Año:
2016
Tipo del documento:
Article
País de afiliación:
Alemania