Emerging roles of the bone morphogenetic protein pathway in cancer: potential therapeutic target for kinase inhibition.

Jiramongkolchai, Pawina; Owens, Philip; Hong, Charles C

Jiramongkolchai, Pawina; Owens, Philip; Hong, Charles C.

Afiliación

Jiramongkolchai P; Department of Medicine, Pharmacology, and Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, U.S.A.
Owens P; Department of Cancer Biology, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232 U.S.A. Philip.owens@vanderbilt.edu.
Hong CC; Department of Medicine, Pharmacology, and Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, U.S.A. Research Medicine, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37212, U.S.A. charles.c.hong@vanderbilt.edu.

Biochem Soc Trans ; 44(4): 1117-34, 2016 08 15.

Article en En | MEDLINE | ID: mdl-27528760

Asunto(s)

Proteínas Morfogenéticas Óseas/metabolismo; Neoplasias/metabolismo; Transducción de Señal; Microambiente Tumoral; Animales; Receptores de Proteínas Morfogenéticas Óseas/metabolismo; Proteínas Morfogenéticas Óseas/antagonistas & inhibidores; Proteínas Morfogenéticas Óseas/genética; Progresión de la Enfermedad; Humanos; Modelos Biológicos; Neoplasias/genética; Neoplasias/terapia

Palabras clave

bone morphogenetic protein (BMP) signalling; cancer; small molecule BMP inhibitors

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas Morfogenéticas Óseas / Microambiente Tumoral / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Biochem Soc Trans Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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