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Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms.
Leszek, Jerzy; Trypka, Elzbieta; Koutsouraki, Euphrosyni; Michmizos, Dimitrios; Yarla, Nagendra Sastry; Tarasov, Vadim V; Ashraf, Ghulam Md; Aliev, Gjumrakch.
Afiliación
  • Leszek J; Department of Psychiatry, Wroclaw Medical University, Pasteura 10, Str.,50-368 Wroclaw, Poland.
  • Trypka E; Department of Psychiatry, Wroclaw Medical University, Pasteura 10, Str.,50-368 Wroclaw, Poland.
  • Koutsouraki E; Medical School, Aristotle University, Thessaloniki, Greece.
  • Michmizos D; Medical School, Aristotle University, Thessaloniki, Greece.
  • Yarla NS; Department of Biochemistry and Bioinformatics, Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh, 530045, India.
  • Tarasov VV; Sechenov First Moscow State Medical University, 119991, Moscow, Russian Federation.
  • Ashraf GM; King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Aliev G; Sechenov First Moscow State Medical University, 119991, Moscow, Russian Federation.
Curr Med Chem ; 25(39): 5389-5394, 2018.
Article en En | MEDLINE | ID: mdl-27593962
ABSTRACT
A number of biological and clinical characteristics typical of late life depression (LLD) have been suggested by recent research findings. The close association of LLD with cognitive impairment is now well documented and evidenced. However, it is still not clear whether it is depression that leads to cognitive decline, and in more severe cases, to dementia. The work presented in this review article suggests that depression and dementia frequently and strongly copresent, even if the causality remains largely opaque.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Depresión / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Curr Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Polonia

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Depresión / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Curr Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Polonia