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Interrogating Metabolism in Brain Cancer.
Salzillo, Travis C; Hu, Jingzhe; Nguyen, Linda; Whiting, Nicholas; Lee, Jaehyuk; Weygand, Joseph; Dutta, Prasanta; Pudakalakatti, Shivanand; Millward, Niki Zacharias; Gammon, Seth T; Lang, Frederick F; Heimberger, Amy B; Bhattacharya, Pratip K.
Afiliación
  • Salzillo TC; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA; The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Hu J; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA; Department of Bioengineering, Rice University, Houston, TX, USA.
  • Nguyen L; The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Whiting N; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Lee J; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Weygand J; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA; The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Dutta P; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Pudakalakatti S; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Millward NZ; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Gammon ST; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Lang FF; Department of Neurosurgery, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Heimberger AB; Department of Neurosurgery, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Bhattacharya PK; Department of Cancer Systems Imaging, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA; The University of Texas Health Science Center at Houston, Houston, TX, USA. Electronic address: PKBhattacharya@mdanderson.org.
Magn Reson Imaging Clin N Am ; 24(4): 687-703, 2016 Nov.
Article en En | MEDLINE | ID: mdl-27742110
ABSTRACT
This article reviews existing and emerging techniques of interrogating metabolism in brain cancer from well-established proton magnetic resonance spectroscopy to the promising hyperpolarized metabolic imaging and chemical exchange saturation transfer and emerging techniques of imaging inflammation. Some of these techniques are at an early stage of development and clinical trials are in progress in patients to establish the clinical efficacy. It is likely that in vivo metabolomics and metabolic imaging is the next frontier in brain cancer diagnosis and assessing therapeutic efficacy; with the combined knowledge of genomics and proteomics a complete understanding of tumorigenesis in brain might be achieved.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Encéfalo / Neoplasias Encefálicas / Espectroscopía de Resonancia Magnética Límite: Humans Idioma: En Revista: Magn Reson Imaging Clin N Am Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Encéfalo / Neoplasias Encefálicas / Espectroscopía de Resonancia Magnética Límite: Humans Idioma: En Revista: Magn Reson Imaging Clin N Am Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos