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Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation.
Yamada, Yuji; Osumi, Tomoo; Imadome, Ken-Ichi; Takahashi, Etsuko; Ohye, Tamae; Yoshikawa, Tetsushi; Tomizawa, Daisuke; Kato, Motohiro; Matsumoto, Kimikazu.
Afiliación
  • Yamada Y; Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
  • Osumi T; Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
  • Imadome KI; Division of Advanced Medicine for Virus Infections, National Research Institute for Child Health and Development, Tokyo, Japan.
  • Takahashi E; Division of Advanced Medicine for Virus Infections, National Research Institute for Child Health and Development, Tokyo, Japan.
  • Ohye T; Department of Molecular Laboratory Medicine, Faculty of Medical Technology, School of Health Sciences, Fujita Health University, Toyoake, Japan.
  • Yoshikawa T; Department of Pediatrics, Fujita Health University, Toyoake, Japan.
  • Tomizawa D; Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
  • Kato M; Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
  • Matsumoto K; Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
Transpl Infect Dis ; 19(1)2017 Feb.
Article en En | MEDLINE | ID: mdl-27859994
ABSTRACT
Chromosomally integrated human herpesvirus 6 (ciHHV-6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ciHHV-6 via cord blood transplantation. Distinguishing transmission of ciHHV-6 from HHV-6 reactivation in cases with high titer of HHV-6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromosomas Humanos Par 22 / Integración Viral / Herpesvirus Humano 6 / Infecciones por Roseolovirus / Acondicionamiento Pretrasplante / Agonistas Mieloablativos / Trasplante de Células Madre de Sangre del Cordón Umbilical / Sangre Fetal Tipo de estudio: Prognostic_studies Límite: Child, preschool / Humans / Male Idioma: En Revista: Transpl Infect Dis Asunto de la revista: TRANSPLANTE Año: 2017 Tipo del documento: Article País de afiliación: Japón

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromosomas Humanos Par 22 / Integración Viral / Herpesvirus Humano 6 / Infecciones por Roseolovirus / Acondicionamiento Pretrasplante / Agonistas Mieloablativos / Trasplante de Células Madre de Sangre del Cordón Umbilical / Sangre Fetal Tipo de estudio: Prognostic_studies Límite: Child, preschool / Humans / Male Idioma: En Revista: Transpl Infect Dis Asunto de la revista: TRANSPLANTE Año: 2017 Tipo del documento: Article País de afiliación: Japón