Effects of tripolyphosphate on cellular uptake and RNA interference efficiency of chitosan-based nanoparticles in Raw 264.7 macrophages.

Xiao, Bo; Ma, Panpan; Ma, Lijun; Chen, Qiubing; Si, Xiaoying; Walter, Lewins; Merlin, Didier

Xiao, Bo; Ma, Panpan; Ma, Lijun; Chen, Qiubing; Si, Xiaoying; Walter, Lewins; Merlin, Didier.

Afiliación

Xiao B; Institute for Clean Energy and Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, PR China; Institute for Biomedical Science, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta 30302, USA. Electronic address: bxiao@gsu.edu.
Ma P; Institute for Clean Energy and Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, PR China.
Ma L; Institute for Clean Energy and Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, PR China.
Chen Q; Institute for Clean Energy and Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, PR China.
Si X; Institute for Clean Energy and Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, PR China.
Walter L; Institute for Biomedical Science, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta 30302, USA.
Merlin D; Institute for Biomedical Science, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta 30302, USA; Atlanta Veterans Affairs Medical Center, Decatur 30033, USA.

J Colloid Interface Sci ; 490: 520-528, 2017 Mar 15.

Article en En | MEDLINE | ID: mdl-27918990

Asunto(s)

Quitosano/análogos & derivados; Macrófagos/metabolismo; Nanopartículas/química; Polifosfatos/química; Compuestos de Amonio Cuaternario/química; Interferencia de ARN; ARN Interferente Pequeño/administración & dosificación; Factor de Necrosis Tumoral alfa/genética; Animales; Quitosano/química; Macrófagos/citología; Ratones; Células RAW 264.7; ARN Interferente Pequeño/genética; ARN Interferente Pequeño/farmacocinética

Palabras clave

Chitosan; Macrophage; N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride; Nanoparticle; RNA interference; Tripolyphosphate

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polifosfatos / Factor de Necrosis Tumoral alfa / ARN Interferente Pequeño / Interferencia de ARN / Quitosano / Nanopartículas / Compuestos de Amonio Cuaternario / Macrófagos Límite: Animals Idioma: En Revista: J Colloid Interface Sci Año: 2017 Tipo del documento: Article

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