Efficacy of the CryoBalloon Focal Ablation System for the eradication of dysplastic Barrett's esophagus islands.
Endoscopy
; 49(2): 169-175, 2017 Feb.
Article
en En
| MEDLINE
| ID: mdl-27997963
ABSTRACT
Background and study aim Cryoablation can be used for the treatment of Barrett's esophagus (BE). A recent dosimetry study, using the CryoBalloon Focal Ablation System (CryoBalloon), demonstrated that 10-second ablations result in complete eradication of BE. However, the efficacy of 10-second ablation in a larger cohort of patients has not been investigated, nor has the potential of precise targeting of specific areas. The aim of the study was to assess the efficacy and performance (i.âe. targeting of BE islands) of a 10-second cryoablation using the CryoBalloon. Results A total of 30 patients were enrolled (worst pathology low grade dysplasia in 14 [47â%], high grade dysplasia in 7 [23â%], early adenocarcinoma in 9 [30â%]). Of the 47 BE islands, 44 (94â%) were adequately targeted. Complete eradication of intestinal metaplasia and dysplasia was observed in 100â% of the completely ablated areas. No stenoses were observed. Conclusion Cryoablation of BE islands using the CryoBalloon is effective. BE islands were effectively targeted.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Esófago de Barrett
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Neoplasias Esofágicas
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Esofagoscopía
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Criocirugía
Tipo de estudio:
Observational_studies
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Endoscopy
Año:
2017
Tipo del documento:
Article
País de afiliación:
Países Bajos