Profiling and identification of (-)-epicatechin metabolites in rats using ultra-high performance liquid chromatography coupled with linear trap-Orbitrap mass spectrometer.

Shang, Zhanpeng; Wang, Fei; Dai, Shengyun; Lu, Jianqiu; Wu, Xiaodan; Zhang, Jiayu

Shang, Zhanpeng; Wang, Fei; Dai, Shengyun; Lu, Jianqiu; Wu, Xiaodan; Zhang, Jiayu.

Afiliación

Shang Z; School of Chinese Pharmacy, Beijing University of Chinese Medicine, No. 6, Wang Jing Zhong Huan Nang Lu South Road, Wangjing, Chaoyang District, Beijing, 100102, China.
Wang F; School of Chinese Pharmacy, Beijing University of Chinese Medicine, No. 6, Wang Jing Zhong Huan Nang Lu South Road, Wangjing, Chaoyang District, Beijing, 100102, China.
Dai S; School of Chinese Pharmacy, Beijing University of Chinese Medicine, No. 6, Wang Jing Zhong Huan Nang Lu South Road, Wangjing, Chaoyang District, Beijing, 100102, China.
Lu J; Library of Beijing University of Chinese Medicine, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 100029, China.
Wu X; Department of Herbal Medicine, School of Basic Medical Sciences, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 100029, China.
Zhang J; Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 100029, China.

Drug Test Anal ; 9(8): 1224-1235, 2017 Aug.

Article en En | MEDLINE | ID: mdl-28042917

Asunto(s)

Antioxidantes/metabolismo; Catequina/metabolismo; Cromatografía Líquida de Alta Presión/métodos; Hipoglucemiantes/metabolismo; Espectrometría de Masa por Ionización de Electrospray/métodos; Animales; Antioxidantes/análisis; Antioxidantes/farmacocinética; Catequina/análisis; Catequina/sangre; Catequina/orina; Minería de Datos/métodos; Glucurónidos/metabolismo; Hidroxilación; Hipoglucemiantes/análisis; Hipoglucemiantes/sangre; Hipoglucemiantes/orina; Masculino; Redes y Vías Metabólicas; Metilación; Ratas

Palabras clave

(−)-epicatechin; mass spectrometer; metabolites; post-acquisition data-mining methods; ultra-high performance liquid chromatography coupled with a linear trap-Orbitrap

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Catequina / Cromatografía Líquida de Alta Presión / Espectrometría de Masa por Ionización de Electrospray / Hipoglucemiantes / Antioxidantes Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Drug Test Anal Asunto de la revista: FARMACOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: China

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