Outcomes and prognostic factors of surgical treatments for brachycephalic obstructive airway syndrome in 3 breeds.
Vet Surg
; 46(2): 271-280, 2017 Feb.
Article
en En
| MEDLINE
| ID: mdl-28146288
ABSTRACT
OBJECTIVE:
To determine prognostic indicators for the surgical treatment of brachycephalic obstructive airway syndrome (BOAS) and to compare the prognosis of 2 multilevel surgical procedures. STUDYDESIGN:
Prospective clinical study. SAMPLE POPULATION Client-owned pugs, French bulldogs, and bulldogs (n = 50).METHODS:
Noninvasive whole-body barometric plethysmography (WBBP) was used to assess respiratory function before, 1 month and 6 months after upper airway corrective surgery. Postoperatively, BOAS indices (ie, ascending severity score generated from WBBP data, 0%-100%) that equaled to or exceeded the cut-off values of BOAS in the diagnostic models were considered to have a "poor prognosis." A multivariate logistic regression was used to assess predictors for prognosis.RESULTS:
The median BOAS indices decreased after surgery (from 76% to 63%, P < .0001), although dogs with indices in this range would still be considered clinically affected. Age (odds ratios [OR] = 0.96, 95% confidence interval [CI] 0.93-0.99, P < .05), body condition (OR = 0.06, 95% CI 0.01-0.39, P < .01), laryngeal collapse (OR = 6.1, 95% CI 1-37.22, P < .05), and surgical techniques (OR = 7.94, 95% CI 1.17-54.01, P < .05) were associated with postoperative prognosis. The multivariate model suggests modified multilevel surgery (MMS) may have a better outcome than traditional multilevel surgery (TMS) (P = .034). The positive predictive value of the logistic model was 84% (95% CI 68-94%) and the area under the receiver operating characteristic (ROC) curve was 89% (95% CI 78-99%, P <.0001).CONCLUSIONS:
Younger age, normal body condition, presence of laryngeal collapse, and treatment with TMS were negative prognostic factors after surgical treatment of BOAS. MMS is recommended, particularly in dogs with a higher probability of poor prognosis.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Craneosinostosis
/
Obstrucción de las Vías Aéreas
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Enfermedades de los Perros
Tipo de estudio:
Evaluation_studies
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Observational_studies
/
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Vet Surg
Año:
2017
Tipo del documento:
Article
País de afiliación:
Reino Unido