Understanding the Intersections between Metabolism and Cancer Biology.
Cell
; 168(4): 657-669, 2017 02 09.
Article
en En
| MEDLINE
| ID: mdl-28187287
ABSTRACT
Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic activities can participate directly in the process of transformation or support the biological processes that enable tumor growth. Exploiting cancer metabolism for clinical benefit requires defining the pathways that are limiting for cancer progression and understanding the context specificity of metabolic preferences and liabilities in malignant cells. Progress toward answering these questions is providing new insight into cancer biology and can guide the more effective targeting of metabolism to help patients.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Redes y Vías Metabólicas
/
Neoplasias
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Cell
Año:
2017
Tipo del documento:
Article