Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis.

Skwark, Marcin J; Croucher, Nicholas J; Puranen, Santeri; Chewapreecha, Claire; Pesonen, Maiju; Xu, Ying Ying; Turner, Paul; Harris, Simon R; Beres, Stephen B; Musser, James M; Parkhill, Julian; Bentley, Stephen D; Aurell, Erik; Corander, Jukka

Skwark, Marcin J; Croucher, Nicholas J; Puranen, Santeri; Chewapreecha, Claire; Pesonen, Maiju; Xu, Ying Ying; Turner, Paul; Harris, Simon R; Beres, Stephen B; Musser, James M; Parkhill, Julian; Bentley, Stephen D; Aurell, Erik; Corander, Jukka.

Afiliación

Skwark MJ; Department of Chemistry, Vanderbilt University, Nashville, TN, United States of America.
Croucher NJ; Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.
Puranen S; Department of Computer Science, Aalto University, Espoo, Finland.
Chewapreecha C; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Pesonen M; Department of Computer Science, Aalto University, Espoo, Finland.
Xu YY; Department of Computer Science, Aalto University, Espoo, Finland.
Turner P; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Harris SR; Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Beres SB; Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom.
Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, and Houston Methodist Hospital, Houston, Texas, United States of America.
Parkhill J; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, and Houston Methodist Hospital, Houston, Texas, United States of America.
Bentley SD; Departments of Pathology and Laboratory Medicine and Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.
Aurell E; Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom.
Corander J; Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom.

PLoS Genet ; 13(2): e1006508, 2017 02.

Article en En | MEDLINE | ID: mdl-28207813

Asunto(s)

Epistasis Genética; Selección Genética/genética; Streptococcus pneumoniae/genética; Streptococcus pyogenes/genética; Resistencia betalactámica/genética; Aminoaciltransferasas/genética; Antibacterianos/uso terapéutico; Proteínas Bacterianas/genética; Redes Reguladoras de Genes/genética; Genética de Población; Genoma Bacteriano/genética; Genómica; Genotipo; Humanos; Pruebas de Sensibilidad Microbiana; Proteínas de Unión a las Penicilinas/química; Proteínas de Unión a las Penicilinas/genética; Peptidil Transferasas/genética; Streptococcus pneumoniae/efectos de los fármacos; Streptococcus pneumoniae/patogenicidad; Streptococcus pyogenes/efectos de los fármacos; Streptococcus pyogenes/patogenicidad; beta-Lactamas/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Selección Genética / Streptococcus pneumoniae / Streptococcus pyogenes / Resistencia betalactámica / Epistasis Genética Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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