Comparison of the AN69ST Membrane versus Citrate-Enriched Dialysate on Clotting Events during Hemodialysis without Systemic Anticoagulation.
Blood Purif
; 44(1): 60-65, 2017.
Article
en En
| MEDLINE
| ID: mdl-28253497
ABSTRACT
BACKGROUND:
The optimal management of anticoagulation in hemodialyzed patients with a high risk of bleeding is controversial.METHODS:
We compared premature termination of dialysis caused by clotting events between AN69ST membranes (G1) and 0.8 mmol/L citrate-enriched dialysate (G2). The number of sessions that had increased venous pressure (VP) and variations in urea-reduction ratio (URR) were analyzed.RESULTS:
Six hundred and two sessions were analyzed in 259 patients 22.4% had sessions that ended prematurely (25% in G1 and 19.1% in G2, p = ns, OR 0.60 [0.34-1.08], p = 0.08). The increase in VP was lower in G2 (23 vs. 70, p < 0.001). URR was higher in G2 (0.56 vs. 0.60, p < 0.001).CONCLUSION:
Clotting events that led to the termination of dialysis were comparable in the 2 groups. However, UUR was better in G2, and the number of patients with increased VP in the sessions was lower in G2. SHORTSUMMARY:
Our study compared the effects of the AN69ST membrane and citrate-enriched dialysate on clotting events during the dialysis of 259 patients with a high risk of bleeding. URR was significantly better and fewer cases of increased VP occurred in the citrate group compared to the AN69 ST group. No significant difference was observed regarding the need to prematurely terminate a dialysis session.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Soluciones para Diálisis
/
Diálisis Renal
/
Ácido Cítrico
/
Membranas Artificiales
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Blood Purif
Año:
2017
Tipo del documento:
Article
País de afiliación:
Francia