Hypoxemia after single-shot anesthesia in common marmosets.
J Med Primatol
; 46(3): 70-74, 2017 06.
Article
en En
| MEDLINE
| ID: mdl-28326553
ABSTRACT
BACKGROUND:
It remains unknown how single-shot anesthesia influences physical parameters, especially respiratory function and blood oxygen level of common marmosets (Callithrix jacchus) which came to be used for laboratory research.METHODS:
We measured blood oxygen levels, both before and after oxygenation, in 13 common marmosets under two single-shot anesthesia conditions ketamine/xylazine/atropine and alphaxalone. RESULTS ANDCONCLUSIONS:
We found that SpO2 values decreased to about 80% in the ketamine/xylazine/atropine protocol and fell just below 90% in the alphaxalone protocol. We observed a clear decrease in PaO2 values under the anesthetized condition compared to the awake condition. Our data indicate that single-shot anesthesia may cause hypoxemia in marmosets. Previous studies on other non-human primate have reported no SpO2 decrease and hypoxemia; thus, our experiment suggests that marmosets may have a more fragile respiratory system and require intensive veterinary care during anesthesia.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Callithrix
/
Anestesia
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Adyuvantes Anestésicos
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Anestésicos
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Hipoxia
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Enfermedades de los Monos
Límite:
Animals
Idioma:
En
Revista:
J Med Primatol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Japón