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Head-to-head comparison of aggressive conventional therapy and three biological treatments and comparison of two de-escalation strategies in patients who respond to treatment: study protocol for a multicenter, randomized, open-label, blinded-assessor, phase 4 study.
Glinatsi, Daniel; Heiberg, Marte S; Rudin, Anna; Nordström, Dan; Haavardsholm, Espen A; Gudbjornsson, Bjorn; Østergaard, Mikkel; Uhlig, Till; Grondal, Gerdur; Hørslev-Petersen, Kim; van Vollenhoven, Ronald; Hetland, Merete L.
Afiliación
  • Glinatsi D; Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Nordre Ringvej 57, DK-2600, Glostrup, Denmark. daniel.glinatsi@gmail.com.
  • Heiberg MS; Department of Rheumatology, Diakonhjemmet Hospital, Box 23 Vinderen, 0219, Oslo, Norway.
  • Rudin A; Clinical Rheumatology Research Centre, Sahlgrenska University Hospital, Gröna Stråket 14, 413 45, Gothenburg, Sweden.
  • Nordström D; Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Gothenburg University, Box 480, 405 30, Gothenburg, Sweden.
  • Haavardsholm EA; Helsinki University Central Hospital and University of Helsinki, Division of Internal Medicine, Stenbäcksgatan 9 A, FIN-00290, Helsinki, Finland.
  • Gudbjornsson B; Department of Rheumatology, Diakonhjemmet Hospital, Box 23 Vinderen, 0219, Oslo, Norway.
  • Østergaard M; Centre for Rheumatology Research, University Hospital, v/Hringbraut, 101, Reykjavik, Iceland.
  • Uhlig T; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Grondal G; Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Nordre Ringvej 57, DK-2600, Glostrup, Denmark.
  • Hørslev-Petersen K; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • van Vollenhoven R; National Advisory Unit for Rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Box 23 Vinderen, 0319, Oslo, Norway.
  • Hetland ML; Department of Rheumatology, University Hospital, Fossvogur, 101, Reykjavik, Iceland.
Trials ; 18(1): 161, 2017 04 04.
Article en En | MEDLINE | ID: mdl-28376912
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Productos Biológicos / Antirreumáticos / Glucocorticoides Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2017 Tipo del documento: Article País de afiliación: Dinamarca
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Productos Biológicos / Antirreumáticos / Glucocorticoides Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2017 Tipo del documento: Article País de afiliación: Dinamarca