Cooperation of neurotrophin receptor TrkB and Her2 in breast cancer cells facilitates brain metastases.

Choy, Cecilia; Ansari, Khairul I; Neman, Josh; Hsu, Sarah; Duenas, Matthew J; Li, Hubert; Vaidehi, Nagarajan; Jandial, Rahul

Choy, Cecilia; Ansari, Khairul I; Neman, Josh; Hsu, Sarah; Duenas, Matthew J; Li, Hubert; Vaidehi, Nagarajan; Jandial, Rahul.

Afiliación

Choy C; Division of Neurosurgery, Beckman Research Institute, City of Hope, 1500 E. Duarte Rd, Duarte, CA, 91010, USA.
Ansari KI; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA, 91010, USA.
Neman J; Division of Neurosurgery, Beckman Research Institute, City of Hope, 1500 E. Duarte Rd, Duarte, CA, 91010, USA.
Hsu S; Department of Neurosurgery, Keck School of Medicine at University of Southern California, Los Angeles, CA, 90089, USA.
Duenas MJ; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, 90089, USA.
Li H; Division of Neurosurgery, Beckman Research Institute, City of Hope, 1500 E. Duarte Rd, Duarte, CA, 91010, USA.
Vaidehi N; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA, 91010, USA.
Jandial R; Department of Immunology, Beckman Research Institute, City of Hope, Duarte, CA, 91010, USA.

Breast Cancer Res ; 19(1): 51, 2017 04 26.

Article en En | MEDLINE | ID: mdl-28446206

Asunto(s)

Neoplasias Encefálicas/genética; Neoplasias de la Mama/genética; Glicoproteínas de Membrana/genética; Receptor ErbB-2/genética; Receptor trkB/genética; Animales; Neoplasias Encefálicas/patología; Neoplasias Encefálicas/secundario; Factor Neurotrófico Derivado del Encéfalo/genética; Neoplasias de la Mama/patología; Línea Celular Tumoral; Proliferación Celular/genética; Dimerización; Femenino; Humanos; Glicoproteínas de Membrana/química; Ratones; Receptor ErbB-2/química; Receptor trkB/química; Transducción de Señal/genética; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

Astrocyte; Brain-derived neurotrophic factor (BDNF); Breast cancer brain metastasis; Cyclotraxin B; Epidermal growth factor receptor 2 (Her2+); Glial cells; Lapatinib; Neural microenvironment; Neurotrophic factor; Neurotrophins; Tropomyosin-related kinase B (TrkB)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Neoplasias de la Mama / Glicoproteínas de Membrana / Receptor ErbB-2 / Receptor trkB Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Breast Cancer Res Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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