Associations of prenatal and early life dietary inflammatory potential with childhood adiposity and cardiometabolic risk in Project Viva.
Pediatr Obes
; 13(5): 292-300, 2018 05.
Article
en En
| MEDLINE
| ID: mdl-28493362
ABSTRACT
BACKGROUND:
Limited information exists regarding the association between early-life diet and cardiometabolic risk.OBJECTIVES:
Examine associations of dietary inflammatory index (DII) in pregnancy and early childhood (3-5 years) with adiposity, blood pressure and metabolic markers in mid-childhood (6-10 years).METHODS:
Among 992 mother-child pairs from Project Viva, a pre-birth cohort, we examined associations of DII scores with outcomes using multivariable linear regression adjusted for child age and sex and maternal age, BMI, education, parity, smoking, race and income.RESULTS:
Mean (SD) maternal DII in pregnancy was -2.6(1.4) units and in child DII in early childhood was 0.3(0.7). Mean mid-childhood BMI z-score was 0.40(0.98) units. In boys only, DII in early childhood was associated with higher BMIz (adjusted ß = 0.16 units per unit DII, 95%CI 0.02, 0.29), waist circumference (0.93 cm; -0.07, 1.92) and skin fold thicknesses (1.12 mm; 0.01, 2.23). Dietary inflammatory index in the highest quartiles during both pregnancy and in early childhood, compared to the lowest quartiles, was associated with higher waist circumference (2.4 cm; 0.14, 4.6) in all children, and BMIz in boys (0.78 units; 0.34, 1.22). Associations with BP and metabolic markers were null.CONCLUSIONS:
A pro-inflammatory diet in pregnancy and early childhood may promote the development of adiposity.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Presión Sanguínea
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Adiposidad
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Conducta Alimentaria
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Obesidad Infantil
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Inflamación
Tipo de estudio:
Etiology_studies
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
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Child
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Child, preschool
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Female
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Humans
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Male
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Pregnancy
Idioma:
En
Revista:
Pediatr Obes
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos