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A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.
Choi, Jiyeon; Xu, Mai; Makowski, Matthew M; Zhang, Tongwu; Law, Matthew H; Kovacs, Michael A; Granzhan, Anton; Kim, Wendy J; Parikh, Hemang; Gartside, Michael; Trent, Jeffrey M; Teulade-Fichou, Marie-Paule; Iles, Mark M; Newton-Bishop, Julia A; Bishop, D Timothy; MacGregor, Stuart; Hayward, Nicholas K; Vermeulen, Michiel; Brown, Kevin M.
Afiliación
  • Choi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
  • Xu M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
  • Makowski MM; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, the Netherlands.
  • Zhang T; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
  • Law MH; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Kovacs MA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
  • Granzhan A; CNRS UMR 9187, INSERM U1196, Institut Curie, PSL Research University and Université Paris Sud, Université Paris Saclay, Orsay, France.
  • Kim WJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
  • Parikh H; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
  • Gartside M; Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
  • Trent JM; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Teulade-Fichou MP; Translational Genomics Research Institute, Phoenix, Arizona, USA.
  • Iles MM; CNRS UMR 9187, INSERM U1196, Institut Curie, PSL Research University and Université Paris Sud, Université Paris Saclay, Orsay, France.
  • Newton-Bishop JA; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
  • Bishop DT; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
  • MacGregor S; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.
  • Hayward NK; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Vermeulen M; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Brown KM; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, the Netherlands.
Nat Genet ; 49(9): 1326-1335, 2017 Sep.
Article en En | MEDLINE | ID: mdl-28759004
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Intrones / Polimorfismo de Nucleótido Simple / Proliferación Celular / Factor de Transcripción Asociado a Microftalmía / Poli(ADP-Ribosa) Polimerasa-1 / Melanocitos Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Intrones / Polimorfismo de Nucleótido Simple / Proliferación Celular / Factor de Transcripción Asociado a Microftalmía / Poli(ADP-Ribosa) Polimerasa-1 / Melanocitos Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos