Investigation of cationized triblock and diblock poly(Îµ-caprolactone)-co-poly(ethylene glycol) copolymers for oral delivery of enoxaparin: In vitro approach.

Charoongchit, Pimchanok; Suksiriworapong, Jiraphong; Mao, Shirui; Sapin-Minet, Anne; Maincent, Philippe; Junyaprasert, Varaporn Buraphacheep

Charoongchit, Pimchanok; Suksiriworapong, Jiraphong; Mao, Shirui; Sapin-Minet, Anne; Maincent, Philippe; Junyaprasert, Varaporn Buraphacheep.

Afiliación

Charoongchit P; Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand. Electronic address: g5136837@student.mahidol.ac.th.
Suksiriworapong J; Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand; Center of Excellence in Innovative Drug Delivery and Nanomedicine, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand. Electronic address: jiraphong.suk@mahidol.ac.th.
Mao S; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: maoshirui@syphu.edu.cn.
Sapin-Minet A; CITHEFOR EA3452 "Drug targets, formulation and preclinical assessment", Faculté de Pharmacie, Université de Lorraine, Nancy 54001, France. Electronic address: anne.sapin@univ-lorraine.fr.
Maincent P; CITHEFOR EA3452 "Drug targets, formulation and preclinical assessment", Faculté de Pharmacie, Université de Lorraine, Nancy 54001, France. Electronic address: philippe.maincent@univ-lorraine.fr.
Junyaprasert VB; Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand; Center of Excellence in Innovative Drug Delivery and Nanomedicine, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand. Electronic address: varaporn.jun@mahidol.ac.th.

Acta Biomater ; 61: 180-192, 2017 10 01.

Article en En | MEDLINE | ID: mdl-28782723

Asunto(s)

Sistemas de Liberación de Medicamentos; Enoxaparina/administración & dosificación; Poliésteres/química; Polietilenglicoles/química; Administración Oral; Células CACO-2; Cationes; Muerte Celular/efectos de los fármacos; Permeabilidad de la Membrana Celular/efectos de los fármacos; Liberación de Fármacos; Enoxaparina/farmacología; Humanos; Imagenología Tridimensional; Tamaño de la Partícula; Propiedades de Superficie; Temperatura

Palabras clave

Cationic copolymer; Enoxaparin; Nanoparticles; Oral delivery; Poly(Îµ-carprolactone)-co-poly(ethylene glycol) copolymers; Polymer architecture

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Poliésteres / Polietilenglicoles / Sistemas de Liberación de Medicamentos / Enoxaparina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Biomater Año: 2017 Tipo del documento: Article

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