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Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660).
Miller, Bruce E; Mayer, Ruth J; Goyal, Navin; Bal, Joanne; Dallow, Nigel; Boyce, Malcolm; Carpenter, Donald; Churchill, Alison; Heslop, Teresa; Lazaar, Aili L.
Afiliación
  • Miller BE; Respiratory Therapy Area Unit, GSK R&D, King of Prussia, Pennsylvania, USA.
  • Mayer RJ; Respiratory Therapy Area Unit, GSK R&D, King of Prussia, Pennsylvania, USA.
  • Goyal N; Clinical Pharmacology Modeling and Simulation, GSK R&D, King of Prussia, Pennsylvania, USA.
  • Bal J; Clinical Pharmacology Sciences and Study Operations, GSK R&D, Stockley Park, UK.
  • Dallow N; Clinical Statistics, GSK R&D, Stockley Park, UK.
  • Boyce M; Hammersmith Medicines Research, Cumberland Avenue, London, UK.
  • Carpenter D; Respiratory Therapy Area Unit, GSK R&D, King of Prussia, Pennsylvania, USA.
  • Churchill A; Hammersmith Medicines Research, Cumberland Avenue, London, UK.
  • Heslop T; Department of In vitro/In vivo Translation, GlaxoSmithKline, Ware, UK.
  • Lazaar AL; Respiratory Therapy Area Unit, GSK R&D, King of Prussia, Pennsylvania, USA.
Br J Clin Pharmacol ; 83(12): 2813-2820, 2017 12.
Article en En | MEDLINE | ID: mdl-28800383
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteasas / Piel / Catepsina C / Dipéptidos / Células Epiteliales Tipo de estudio: Clinical_trials Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteasas / Piel / Catepsina C / Dipéptidos / Células Epiteliales Tipo de estudio: Clinical_trials Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos