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Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial.
Townsend, Raymond R; Mahfoud, Felix; Kandzari, David E; Kario, Kazuomi; Pocock, Stuart; Weber, Michael A; Ewen, Sebastian; Tsioufis, Konstantinos; Tousoulis, Dimitrios; Sharp, Andrew S P; Watkinson, Anthony F; Schmieder, Roland E; Schmid, Axel; Choi, James W; East, Cara; Walton, Anthony; Hopper, Ingrid; Cohen, Debbie L; Wilensky, Robert; Lee, David P; Ma, Adrian; Devireddy, Chandan M; Lea, Janice P; Lurz, Philipp C; Fengler, Karl; Davies, Justin; Chapman, Neil; Cohen, Sidney A; DeBruin, Vanessa; Fahy, Martin; Jones, Denise E; Rothman, Martin; Böhm, Michael.
Afiliación
  • Townsend RR; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: townsend@upenn.edu.
  • Mahfoud F; Department of Internal Medicine III, University Hospital of Saarland, Saarland University, Homburg/Saar, Germany; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Kandzari DE; Piedmont Heart Institute, Atlanta, GA, USA.
  • Kario K; Jichi Medical University School of Medicine, Tochigi, Japan.
  • Pocock S; London School of Hygiene & Tropical Medicine, London, UK.
  • Weber MA; SUNY Downstate College of Medicine, Brooklyn, NY, USA.
  • Ewen S; Department of Internal Medicine III, University Hospital of Saarland, Saarland University, Homburg/Saar, Germany.
  • Tsioufis K; University of Athens, Hippocration Hospital, Athens, Greece.
  • Tousoulis D; University of Athens, Hippocration Hospital, Athens, Greece.
  • Sharp ASP; The Royal Devon and Exeter Hospital, Exeter, UK.
  • Watkinson AF; The Royal Devon and Exeter Hospital, Exeter, UK.
  • Schmieder RE; University Hospital Erlangen, Erlangen, Germany.
  • Schmid A; University Hospital Erlangen, Erlangen, Germany.
  • Choi JW; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, TX, USA.
  • East C; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, TX, USA.
  • Walton A; The Alfred Hospital and Monash University, Melbourne, VIC, Australia.
  • Hopper I; The Alfred Hospital, Melbourne, VIC, Australia.
  • Cohen DL; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Medtronic PLC, Santa Rosa, CA, USA.
  • Wilensky R; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Lee DP; Stanford Hospital & Clinics, Stanford, CA, USA.
  • Ma A; Stanford Hospital & Clinics, Stanford, CA, USA.
  • Devireddy CM; Emory University School of Medicine, Atlanta, GA, USA.
  • Lea JP; Emory University School of Medicine, Atlanta, GA, USA.
  • Lurz PC; University of Leipzig-Heart Center, Leipzig, Germany.
  • Fengler K; University of Leipzig-Heart Center, Leipzig, Germany.
  • Davies J; Imperial College and Hammersmith Hospital, Imperial, London, UK.
  • Chapman N; Imperial College and Hammersmith Hospital, Imperial, London, UK.
  • Cohen SA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Medtronic PLC, Santa Rosa, CA, USA.
  • DeBruin V; Medtronic PLC, Santa Rosa, CA, USA.
  • Fahy M; Medtronic PLC, Santa Rosa, CA, USA.
  • Jones DE; Medtronic PLC, Santa Rosa, CA, USA.
  • Rothman M; Medtronic PLC, Santa Rosa, CA, USA; Barts Health Trust, London, UK.
  • Böhm M; Department of Internal Medicine III, University Hospital of Saarland, Saarland University, Homburg/Saar, Germany.
Lancet ; 390(10108): 2160-2170, 2017 Nov 11.
Article en En | MEDLINE | ID: mdl-28859944

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Simpatectomía / Resistencia a Medicamentos / Ablación por Catéter / Hipertensión Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte / Europa / Oceania Idioma: En Revista: Lancet Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Simpatectomía / Resistencia a Medicamentos / Ablación por Catéter / Hipertensión Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte / Europa / Oceania Idioma: En Revista: Lancet Año: 2017 Tipo del documento: Article