Meta-analysis of accuracy of intraocular lens power calculation formulas in short eyes.
Clin Exp Ophthalmol
; 46(4): 356-363, 2018 05.
Article
en En
| MEDLINE
| ID: mdl-28887901
ABSTRACT
IMPORTANCE Intraocular lens (IOL) power selection is a critical factor affecting visual outcome after IOL implantation in short eyes. Many formulas have been developed to achieve a precise prediction of the IOL power. However, controversy regarding the accuracy remains. BACKGROUND:
To investigate the accuracy of different IOL power calculation formulas in short eyes.DESIGN:
Meta-analysis.PARTICIPANTS:
Patients with the axial length of eyes less than 22 mm from previously reported studies.METHODS:
A comprehensive search in Pubmed, EMBASE, Cochrane Data Base of Systematic Reviews and the Cochrane Central Register of Controlled Trials was conducted by October 2016. We assessed the methodological quality using a modified QUADAS-2 tool and performed analysis on weighted mean differences of mean absolute errors (MAE) among different formulas. MAIN OUTCOMESMEASURES:
The between-group difference of MAE was evaluated with weighted mean difference and 95% confidence intervals.RESULTS:
Ten observational studies, involving 1161 eyes, were enrolled to compare six formulas Haigis, Holladay 2, Hoffer Q, Holladay 1, SRK/T and SRK II. Among them, the Holladay 2 introduced the smallest overall MAE (0.496D) without statistical significance. The difference of MAE is statistically significant between Haigis and Hoffer Q (mean difference = -0.07D, P = 0.003), Haigis and SRK/T (mean difference = -0.07D, P = 0.009), Haigis and SRK II (mean difference = -0.41D, P = 0.01). For publication bias and small-study effect, neither funnel plot nor egger's test detected statistical finding. CONCLUSION AND RELEVANCE The overall evidence from the studies confirmed the superiority of Haigis over Hoffer Q, SRK/T and SRK II in prediction IOL power in short eyes.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Refracción Ocular
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Agudeza Visual
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Biometría
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Óptica y Fotónica
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Lentes Intraoculares
Tipo de estudio:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
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Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Clin Exp Ophthalmol
Asunto de la revista:
OFTALMOLOGIA
Año:
2018
Tipo del documento:
Article