Muscular contraction frequency does not affect plasma homocysteine concentration in response to energy expenditure- and intensity-matched acute exercise in sedentary males.
Appl Physiol Nutr Metab
; 43(2): 107-112, 2018 Feb.
Article
en En
| MEDLINE
| ID: mdl-28910538
ABSTRACT
Acute exercise seems to increase total plasma homocysteine (tHcy); since this variable associated with cardiovascular risk, it is important to understand the determinants of its response to all types of exercise. The aim of this study was to examine the impact of cycling at 2 different rates of muscle contraction on the complete tHcy kinetics. Eight young sedentary males were required to complete 2 isocaloric (400 kcal) acute exercise trials at 50% peak oxygen uptake on separate occasions at 50 or 80 rpm. Blood samples were drawn at different points before (4 h before exercise and immediately before exercise), during (10, 20, 30, 45, and 60 min during exercise), and after exercise (immediately and 19 h after exercise). Dietary and lifestyle factors were controlled during the research. Maximum tHcy occurred during exercise for both conditions (50 rpm 11.4 ± 2.7 µmol·L-1; 80 rpm 10.8 ± 3.2 µmol·L-1). From this point onwards tHcy declined until the cessation of exercise and continued descending below pre-exercise values at 19 h postexercise (p < 0.05). No hyperhomocysteinemia were observed at any sampling point in both trials. In conclusion, the different muscular contraction frequency during exercise has no impact on tHcy during an acute bout of exercise in sedentary individuals, when at least 400 kcal are spent during exercise and the nutritional status for folate, B12, and B6 is adequate. This information is relevant to further inform healthy exercise prescription, not only in terms of duration and intensity of exercise, but also taking into account frequency of contraction.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ejercicio Físico
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Metabolismo Energético
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Homocisteína
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Contracción Muscular
Tipo de estudio:
Clinical_trials
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Health_economic_evaluation
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Appl Physiol Nutr Metab
Asunto de la revista:
CIENCIAS DA NUTRICAO
/
FISIOLOGIA
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MEDICINA ESPORTIVA
/
METABOLISMO
Año:
2018
Tipo del documento:
Article
País de afiliación:
España