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Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units.
Choi, Peter J; Sutherland, Hamish S; Tong, Amy S T; Blaser, Adrian; Franzblau, Scott G; Cooper, Christopher B; Lotlikar, Manisha U; Upton, Anna M; Guillemont, Jerome; Motte, Magali; Queguiner, Laurence; Andries, Koen; Van den Broeck, Walter; Denny, William A; Palmer, Brian D.
Afiliación
  • Choi PJ; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Sutherland HS; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Tong AST; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Blaser A; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Cooper CB; Global Alliance for TB Drug Development, 40 Wall St, New York 10005, USA.
  • Lotlikar MU; Global Alliance for TB Drug Development, 40 Wall St, New York 10005, USA.
  • Upton AM; Global Alliance for TB Drug Development, 40 Wall St, New York 10005, USA.
  • Guillemont J; Medicinal Chemistry Department (Infectious Diseases), Janssen Pharmaceuticals, Campus de Maigremont, BP315, 27106 Val de Reuil Cedex, France.
  • Motte M; Medicinal Chemistry Department (Infectious Diseases), Janssen Pharmaceuticals, Campus de Maigremont, BP315, 27106 Val de Reuil Cedex, France.
  • Queguiner L; Medicinal Chemistry Department (Infectious Diseases), Janssen Pharmaceuticals, Campus de Maigremont, BP315, 27106 Val de Reuil Cedex, France.
  • Andries K; Janssen Infectious Diseases BVBA, Beerse, Belgium.
  • Van den Broeck W; Janssen Infectious Diseases BVBA, Beerse, Belgium.
  • Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address: b.denny@auckland.ac.nz.
  • Palmer BD; Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Maurice Wilkins Centre, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Bioorg Med Chem Lett ; 27(23): 5190-5196, 2017 12 01.
Article en En | MEDLINE | ID: mdl-29107541
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Diarilquinolinas / Compuestos Heterocíclicos / Antituberculosos Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Nueva Zelanda
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Diarilquinolinas / Compuestos Heterocíclicos / Antituberculosos Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Nueva Zelanda