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A role for bacterial urease in gut dysbiosis and Crohn's disease.
Ni, Josephine; Shen, Ting-Chin David; Chen, Eric Z; Bittinger, Kyle; Bailey, Aubrey; Roggiani, Manuela; Sirota-Madi, Alexandra; Friedman, Elliot S; Chau, Lillian; Lin, Andrew; Nissim, Ilana; Scott, Justin; Lauder, Abigail; Hoffmann, Christopher; Rivas, Gloriany; Albenberg, Lindsey; Baldassano, Robert N; Braun, Jonathan; Xavier, Ramnik J; Clish, Clary B; Yudkoff, Marc; Li, Hongzhe; Goulian, Mark; Bushman, Frederic D; Lewis, James D; Wu, Gary D.
Afiliación
  • Ni J; Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Shen TD; Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Chen EZ; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Bittinger K; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Bailey A; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Roggiani M; Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Sirota-Madi A; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, MA 02142, USA.
  • Friedman ES; Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Chau L; Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lin A; Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Nissim I; Division of Child Development, Rehabilitation, and Metabolic Disease, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Scott J; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, MA 02142, USA.
  • Lauder A; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Hoffmann C; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Rivas G; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Albenberg L; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
  • Baldassano RN; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
  • Braun J; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
  • Xavier RJ; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, MA 02142, USA.
  • Clish CB; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
  • Yudkoff M; Center for Microbiome Informatics and Therapeutics, MIT, Cambridge, MA 02139, USA.
  • Li H; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, MA 02142, USA.
  • Goulian M; Division of Child Development, Rehabilitation, and Metabolic Disease, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Bushman FD; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lewis JD; Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Wu GD; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sci Transl Med ; 9(416)2017 Nov 15.
Article en En | MEDLINE | ID: mdl-29141885

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Ureasa / Enfermedad de Crohn / Disbiosis / Microbioma Gastrointestinal Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Ureasa / Enfermedad de Crohn / Disbiosis / Microbioma Gastrointestinal Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos