Toward Optimizing Cervical Vestibular Evoked Myogenic Potentials (cVEMP): Combining Air-Bone Gap and cVEMP Thresholds to Improve Diagnosis of Superior Canal Dehiscence.
Otol Neurotol
; 39(2): 212-220, 2018 02.
Article
en En
| MEDLINE
| ID: mdl-29210947
ABSTRACT
OBJECTIVE:
To develop a novel approach combining low-frequency air-bone gap (ABG) and cervical vestibular evoked myogenic potential (cVEMP) thresholds to improve screening for superior canal dehiscence (SCD) syndrome. STUDYDESIGN:
Retrospective study.SETTING:
Tertiary care center. PATIENTS One hundred forty patients with SCD and 21 healthy age-matched controls were included. Ears for each patient were divided into three groups based on computed tomography (CT)findings:
1) dehiscent, 2) thin, or 3) unaffected. MAIN OUTCOMEMEASURES:
cVEMP and audiometric thresholds were analyzed and differences among groups were evaluated.RESULTS:
We define the third window indicator (TWI) as the cVEMP thresholds at 500, 750, and 1000âHz adjusted for the ABG at 250âHz (i.e., subtracting ABG from cVEMP threshold). The TWI differentiates between dehiscent and nondehiscent control ears with a sensitivity of 82% and specificity of 100%, corresponding to a positive predictive value of 100%. ABGs and cVEMP thresholds were similar for healthy controls and patients with thin bone over the superior canal.CONCLUSION:
This is the largest study to date examining the usefulness of cVEMPs in the diagnosis of SCD. Our "third window indicator" (TWI) combines cVEMP thresholds with the ABG at 250âHz to improve the ability to screen patients with SCD symptoms.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Potenciales Vestibulares Miogénicos Evocados
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Enfermedades del Laberinto
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Otol Neurotol
Asunto de la revista:
NEUROLOGIA
/
OTORRINOLARINGOLOGIA
Año:
2018
Tipo del documento:
Article