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Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
Van Skike, Candice E; Jahrling, Jordan B; Olson, Angela B; Sayre, Naomi L; Hussong, Stacy A; Ungvari, Zoltan; Lechleiter, James D; Galvan, Veronica.
Afiliación
  • Van Skike CE; Department of Cellular and Integrative Physiology and Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio , San Antonio, Texas.
  • Jahrling JB; Department of Cellular and Integrative Physiology and Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio , San Antonio, Texas.
  • Olson AB; Department of Cellular and Integrative Physiology and Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio , San Antonio, Texas.
  • Sayre NL; Department of Neurosurgery, University of Texas Health San Antonio , San Antonio, Texas.
  • Hussong SA; Department of Veterans Affairs, South Texas Veterans Health Care System, San Antonio, Texas.
  • Ungvari Z; Department of Cellular and Integrative Physiology and Barshop Institute for Longevity and Aging Studies, University of Texas Health San Antonio , San Antonio, Texas.
  • Lechleiter JD; Department of Veterans Affairs, South Texas Veterans Health Care System, San Antonio, Texas.
  • Galvan V; Department of Geriatric Medicine and Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center , Oklahoma City, Oklahoma.
Am J Physiol Heart Circ Physiol ; 314(4): H693-H703, 2018 04 01.
Article en En | MEDLINE | ID: mdl-29351469
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Conducta Animal / Barrera Hematoencefálica / Demencia Vascular / Cognición / Sirolimus / Inhibidores de Proteínas Quinasas / Serina-Treonina Quinasas TOR / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Am J Physiol Heart Circ Physiol Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2018 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Conducta Animal / Barrera Hematoencefálica / Demencia Vascular / Cognición / Sirolimus / Inhibidores de Proteínas Quinasas / Serina-Treonina Quinasas TOR / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Am J Physiol Heart Circ Physiol Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2018 Tipo del documento: Article