Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in <i>VHL</i>-deficient human renal cell carcinoma.

Scanlon, Susan E; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M

Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma.

Scanlon, Susan E; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M.

Afiliación

Scanlon SE; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Hegan DC; Department of Experimental Pathology, Yale University School of Medicine, New Haven, CT, USA.
Sulkowski PL; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Glazer PM; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.

Oncotarget ; 9(4): 4647-4660, 2018 Jan 12.

Article en En | MEDLINE | ID: mdl-29435132

Palabras clave

DNA repair; PARP inhibitor; homologous recombination; hypoxia; von Hippel-Lindau (VHL)

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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Oncotarget Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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