Risk factors for platelet transfusion in glioblastoma surgery.
J Clin Neurosci
; 50: 93-97, 2018 Apr.
Article
en En
| MEDLINE
| ID: mdl-29452964
ABSTRACT
The objectives of this study are to identify risk factors for and to evaluate clinical outcomes of platelet transfusion in glioblastoma surgery. The medical records of adult patients who underwent craniotomy for glioblastoma resection at a single academic medical center were retrospectively reviewed. We stratified patients into 2 groups those who were transfused at least 1 unit of platelets intraoperatively or postoperatively (no more than 7â¯days after surgery), and those who were not transfused with platelets. Through the use of a 13 matched cohort analysis, we compared complications, length of stay, discharge disposition, and mortality, across groups. One hundred and five consecutive adult patients were included in this study. Thirteen patients (12.38%) received platelet transfusions. Prior antiplatelet therapy (odds ratio [OR] 8.21, 95% confidence interval [CI] 2.36-28.58), preoperative platelet count less than 200,000â¯cells/µL (OR 8.46, 95% CI 2.16-33.22), and longer operative times (OR 1.73, 95% CI 1.10-2.72) were significant risk factors for platelet transfusion. There were no significant differences in the outcomes of interest in the matched cohort analysis.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Encefálicas
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Transfusión de Plaquetas
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Glioblastoma
Tipo de estudio:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Clin Neurosci
Asunto de la revista:
NEUROLOGIA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos