Chloroform fraction of Foeniculum vulgare induced ROS mediated, mitochondria-caspase-dependent apoptotic pathway in MCF-7, human breast cancer cell line.

Syed, Fareeduddin Quadri; Elkady, Ayman I; Mohammed, Furkhan Ahmed; Mirza, Muqtadir Baig; Hakeem, Khalid Rehman; Alkarim, Saleh

Syed, Fareeduddin Quadri; Elkady, Ayman I; Mohammed, Furkhan Ahmed; Mirza, Muqtadir Baig; Hakeem, Khalid Rehman; Alkarim, Saleh.

Afiliación

Syed FQ; Department of Biological Science, Faculty of Science, King Abdulaziz University (KAU), PO Box 80203, Jeddah, Saudi Arabia. Electronic address: fareed2619@gmail.com.
Elkady AI; Department of Biological Science, Faculty of Science, King Abdulaziz University (KAU), PO Box 80203, Jeddah, Saudi Arabia; Zoology Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: aymanelkady2009@gmail.com.
Mohammed FA; Department of Biological Science, Faculty of Science, King Abdulaziz University (KAU), PO Box 80203, Jeddah, Saudi Arabia. Electronic address: furkhanmohammed11@gmail.com.
Mirza MB; Department of Biological Science, Faculty of Science, King Abdulaziz University (KAU), PO Box 80203, Jeddah, Saudi Arabia. Electronic address: muqtadirbaig786@gmail.com.
Hakeem KR; Department of Biological Science, Faculty of Science, King Abdulaziz University (KAU), PO Box 80203, Jeddah, Saudi Arabia. Electronic address: kur.hakeem@gmail.com.
Alkarim S; Department of Biological Science, Faculty of Science, King Abdulaziz University (KAU), PO Box 80203, Jeddah, Saudi Arabia. Electronic address: skarim@kau.edu.sa.

J Ethnopharmacol ; 218: 16-26, 2018 May 23.

Article en En | MEDLINE | ID: mdl-29474902

Asunto(s)

Antineoplásicos Fitogénicos/farmacología; Foeniculum; Extractos Vegetales/farmacología; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/metabolismo; Caspasa 3/metabolismo; Caspasa 9/metabolismo; Puntos de Control del Ciclo Celular/efectos de los fármacos; Proliferación Celular/efectos de los fármacos; Cloroformo/química; Ensayo Cometa; Humanos; Células MCF-7; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Mitocondrias/efectos de los fármacos; Mitocondrias/metabolismo; Mitocondrias/fisiología; Especies Reactivas de Oxígeno/metabolismo; Semillas; Solventes/química

Palabras clave

Apoptosis; Fennel; Foeniculum vulgare; Mitochondrial pathway; Reactive oxygen species

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Extractos Vegetales / Foeniculum / Antineoplásicos Fitogénicos Límite: Humans Idioma: En Revista: J Ethnopharmacol Año: 2018 Tipo del documento: Article

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