Tuberous Sclerosis Complex with Gingival Enlargement in an Adolescent.
J Coll Physicians Surg Pak
; 28(3): S16-S18, 2018 Mar.
Article
en En
| MEDLINE
| ID: mdl-29482692
ABSTRACT
Tuberous sclerosis complex (TSC) is an autosomal dominant, multisystem genetic disorder. It is characterised by formation of benign hamartomas, neurofibromas, and angiofibromas located in different organs. We describe a case of a 13-year boy who complained of gingival enlargement. Clinical examination showed distinctive dermatological signs like hypopigmented macules, shagreen plaques, miliary fibromas, fibrous plaques and multiple angiofibromas. Oral manifestation included localised gingival enlargement. Gingivectomy was performed and the excised tissue was submitted for histopathological examination. The microscopic examination of gingival tissue revealed multiple bundles of collagen fibres with proliferating fibroblast and multiple proliferating blood vessels in the connective tissue. The clinical and histopathological findings were consistent with gingival angiofibromas of TSC. Gingivectomy allowed the patient to have better function and aesthetics. Periodontal examination in conjunction with dermatological examination is important for early diagnosis of TSC.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Esclerosis Tuberosa
/
Sobrecrecimiento Gingival
Tipo de estudio:
Screening_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
J Coll Physicians Surg Pak
Asunto de la revista:
MEDICINA
Año:
2018
Tipo del documento:
Article
País de afiliación:
India