Impact of estrogens and estrogen receptor-α in brain lipid metabolism.
Am J Physiol Endocrinol Metab
; 315(1): E7-E14, 2018 07 01.
Article
en En
| MEDLINE
| ID: mdl-29509437
ABSTRACT
Estrogens and their receptors play key roles in regulating body weight, energy expenditure, and metabolic homeostasis. It is known that lack of estrogens promotes increased food intake and induces the expansion of adipose tissues, for which much is known. An area of estrogenic research that has received less attention is the role of estrogens and their receptors in influencing intermediary lipid metabolism in organs such as the brain. In this review, we highlight the actions of estrogens and their receptors in regulating their impact on modulating fatty acid content, utilization, and oxidation through their direct impact on intracellular signaling cascades within the central nervous system.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Química Encefálica
/
Receptor alfa de Estrógeno
/
Estrógenos
/
Metabolismo de los Lípidos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Am J Physiol Endocrinol Metab
Asunto de la revista:
ENDOCRINOLOGIA
/
FISIOLOGIA
/
METABOLISMO
Año:
2018
Tipo del documento:
Article
País de afiliación:
Chile