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UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells.
Wegner, Marthe-Susanna; Schömel, Nina; Gruber, Lisa; Örtel, Stephanie Beatrice; Kjellberg, Matti Aleksi; Mattjus, Peter; Kurz, Jennifer; Trautmann, Sandra; Peng, Bing; Wegner, Martin; Kaulich, Manuel; Ahrends, Robert; Geisslinger, Gerd; Grösch, Sabine.
Afiliación
  • Wegner MS; pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, House 74, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany. wegner@med.uni-frankfurt.de.
  • Schömel N; pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, House 74, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany.
  • Gruber L; pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, House 74, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany.
  • Örtel SB; pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, House 74, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany.
  • Kjellberg MA; Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, Artillerigatan 6A, III, BioCity, 20520, Turku, Finland.
  • Mattjus P; Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, Artillerigatan 6A, III, BioCity, 20520, Turku, Finland.
  • Kurz J; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology (TMP), Frankfurt am Main, Germany.
  • Trautmann S; pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, House 74, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany.
  • Peng B; Leibniz-Institut für Analytische Wissenschaften, ISAS e. V., Otto-Hahn-Straße 6b, 44227, Dortmund, Germany.
  • Wegner M; Institute of Biochemistry II, Johann Wolfgang Goethe University, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany.
  • Kaulich M; Institute of Biochemistry II, Johann Wolfgang Goethe University, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany.
  • Ahrends R; Leibniz-Institut für Analytische Wissenschaften, ISAS e. V., Otto-Hahn-Straße 6b, 44227, Dortmund, Germany.
  • Geisslinger G; pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, House 74, Theodor Stern-Kai 7, 60590, Frankfurt am Main, Germany.
  • Grösch S; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology (TMP), Frankfurt am Main, Germany.
Cell Mol Life Sci ; 75(18): 3393-3410, 2018 Sep.
Article en En | MEDLINE | ID: mdl-29549423
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Resistencia a Antineoplásicos / Proliferación Celular / Proteínas Proto-Oncogénicas c-akt / Glucosiltransferasas Límite: Female / Humans Idioma: En Revista: Cell Mol Life Sci Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Resistencia a Antineoplásicos / Proliferación Celular / Proteínas Proto-Oncogénicas c-akt / Glucosiltransferasas Límite: Female / Humans Idioma: En Revista: Cell Mol Life Sci Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article País de afiliación: Alemania