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Recommendations for the use of Rituximab in neuromyelitis optica spectrum disorders
Ciron, J; Audoin, B; Bourre, B; Brassat, D; Durand-Dubief, F; Laplaud, D; Maillart, E; Papeix, C; Vukusic, S; Zephir, H; Marignier, R; Collongues, N.
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  • Ciron J; Pôle de neurosciences, department of neurology, hôpital Pierre-Paul-Riquet, university hospital of Toulouse, place du Dr-Baylac, 31059 Toulouse Cedex 9, France; Pôle neurosciences locomoteur, department of neurology, university hospital of Poitiers, 2, rue de la Milétrie, 86021 Poitiers Cedex, Franc
  • Audoin B; Pôle de neurosciences cliniques, department of beurology, hôpital de la Timone, AP-HM, 13005 Marseille, France; CNRS, CRMBM UMR 7339, Aix-Marseille University, 13005 Marseille, France.
  • Bourre B; Department of neurology, university hospital of Rouen, 76000 Rouen, France.
  • Brassat D; Pôle de neurosciences, department of neurology, hôpital Pierre-Paul-Riquet, university hospital of Toulouse, place du Dr-Baylac, 31059 Toulouse Cedex 9, France; UMR 1043, University Toulouse III, 31400 Toulouse, France.
  • Durand-Dubief F; Department of neurology, Sclérose en Plaques, pathologies de la myéline et neuro-inflammation, hôpital neurologique Pierre-Wertheimer, hospices civils de Lyon, 69677 Lyon, France.
  • Laplaud D; Department of neurology, university hospital of Nantes, 44093 Nantes, France.
  • Maillart E; Department of neurology, Pitié-Salpêtrière Hospital, AP-HP, 75013 Paris, France.
  • Papeix C; Department of neurology, Pitié-Salpêtrière Hospital, AP-HP, 75013 Paris, France.
  • Vukusic S; Department of neurology, Sclérose en Plaques, pathologies de la myéline et neuro-inflammation, hôpital neurologique Pierre-Wertheimer, hospices civils de Lyon, 69677 Lyon, France; Inserm U1028 CNRS UMR 5292, Observatoire français de la Sclérose en Plaques, centre des neurosciences de Lyon, 69003 Lyo
  • Zephir H; Department of neurology, university hospital of Lille, 59037 Lille, France.
  • Marignier R; Department of neurology, Sclérose en Plaques, pathologies de la myéline et neuro-inflammation, hôpital neurologique Pierre-Wertheimer, hospices civils de Lyon, 69677 Lyon, France; Inserm U1028 CNRS UMR 5292, FLUID Team, faculté de médecine Laennec, centre de recherche en neurosciences de Lyon, 69008
  • Collongues N; Department of neurology, university hospital of Strasbourg, 67200 Strasbourg, France; Clinical Investigation Center, Inserm U1434, university hospital of Strasbourg, 67200 Strasbourg, France; Biopathology of Myelin, neuroprotection and therapeutic Strategies, Inserm U1119, university hospital of Str
Rev Neurol (Paris) ; 174(4): 255-264, 2018 04.
Article en En | MEDLINE | ID: mdl-29606320
ABSTRACT
There is growing evidence of a preventive effect of Rituximab (RTX) in neuromyelitis optica spectrum disorders (NMO-SD). This monoclonal antibody against CD20 is becoming the most widely used preventive therapy in NMO-SD, as a first-line therapy or as a rescue therapy. Nevertheless, considerable heterogeneity still exists concerning the pre-treatment work-up, the vaccinations required before and under treatment, the number and dosage of infusions, prevention of the risk of infusion-related reactions, prevention of infections under treatment, and frequency of therapeutic cycles. Thanks to a collaborative work among NMO-SD experts belonging to the NOMADMUS project, we provide here recommendations for all these topics concerning RTX use in NMO-SD.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neuromielitis Óptica / Rituximab Tipo de estudio: Diagnostic_studies / Guideline Límite: Humans Idioma: En Revista: Rev Neurol (Paris) Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neuromielitis Óptica / Rituximab Tipo de estudio: Diagnostic_studies / Guideline Límite: Humans Idioma: En Revista: Rev Neurol (Paris) Año: 2018 Tipo del documento: Article