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Two new triterpenes from the roots of Pfaffia glomerata.
Lian, Lian; Feng, Yuan; Li, Yan-Wu; Bei, Bei; Tang, Ye-Tian; Wang, Hao; Feng, Qing-Mei; Chen, Gang.
Afiliación
  • Lian L; b School of Biopharmaceutical and Chemical Engineering , Liaoning Instituent of Science and Technology , Benxi 117004 , China.
  • Feng Y; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Li YW; c Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education , Shenyang 110016 , China.
  • Bei B; d Pi-Wei Institute , Guangzhou University of Chinese Medicine , Guangzhou 510405 , China.
  • Tang YT; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Wang H; c Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education , Shenyang 110016 , China.
  • Feng QM; a School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Chen G; c Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education , Shenyang 110016 , China.
J Asian Nat Prod Res ; 21(5): 442-448, 2019 May.
Article en En | MEDLINE | ID: mdl-29607660
Pfaffia paniculata is a commercialized dietary supplement used as the substitute for the Asian ginseng in Brazil. We conducted the systematic isolation of the EtOAc fraction with anti-inflammatory effect and two new triterpenoids, along with 26 known compounds were characterized by means of MS and NMR analysis. Interestingly, the new compound 1 is the first seco-ring triterpenoid reported in the Pfaffia genus. Furthermore, among the known compounds, 14 and 15 exhibited anti-inflammatory activity in Caco-2 cells, but two new compounds showed no anti-inflammatory.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triterpenos / Raíces de Plantas / Amaranthaceae Límite: Humans Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triterpenos / Raíces de Plantas / Amaranthaceae Límite: Humans Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China