Optimized phospholipid-based nanoparticles for inner ear drug delivery and therapy.

Yang, Keum-Jin; Son, Jihwan; Jung, So Young; Yi, Gawon; Yoo, Jihye; Kim, Dong-Kee; Koo, Heebeom

Yang, Keum-Jin; Son, Jihwan; Jung, So Young; Yi, Gawon; Yoo, Jihye; Kim, Dong-Kee; Koo, Heebeom.

Afiliación

Yang KJ; Clinical Research Institute, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Republic of Korea.
Son J; Department of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jung SY; Clinical Research Institute, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Republic of Korea.
Yi G; Department of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Yoo J; Department of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Kim DK; Department of Otolaryngology, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Republic of Korea. Electronic address: cider12@catholic.ac.kr.
Koo H; Department of Medical Lifescience, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Catholic Photomedicine Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: hbkoo@catholic.ac.kr.

Biomaterials ; 171: 133-143, 2018 07.

Article en En | MEDLINE | ID: mdl-29689410

Asunto(s)

Sistemas de Liberación de Medicamentos; Oído Interno/patología; Nanopartículas/química; Fosfolípidos/química; Animales; Muerte Celular/efectos de los fármacos; Línea Celular; Dexametasona/administración & dosificación; Dexametasona/farmacología; Modelos Animales de Enfermedad; Portadores de Fármacos/química; Oído Interno/efectos de los fármacos; Humanos; Masculino; Ratones Endogámicos C57BL; Nanopartículas/ultraestructura; Polietilenglicoles/química

Palabras clave

Dexamethasone; Drug delivery; Hearing loss; Inner ear; Nanoparticle; Ototoxicity

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfolípidos / Sistemas de Liberación de Medicamentos / Nanopartículas / Oído Interno Límite: Animals / Humans / Male Idioma: En Revista: Biomaterials Año: 2018 Tipo del documento: Article

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