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Targeting the Mevalonate Pathway Suppresses VHL-Deficient CC-RCC through an HIF-Dependent Mechanism.
Thompson, Jordan M; Alvarez, Alejandro; Singha, Monika K; Pavesic, Matthew W; Nguyen, Quy H; Nelson, Luke J; Fruman, David A; Razorenova, Olga V.
Afiliación
  • Thompson JM; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California.
  • Alvarez A; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California.
  • Singha MK; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California.
  • Pavesic MW; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California.
  • Nguyen QH; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California.
  • Nelson LJ; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California.
  • Fruman DA; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California.
  • Razorenova OV; Molecular Biology and Biochemistry Department, University of California Irvine, Irvine, California. olgar@uci.edu.
Mol Cancer Ther ; 17(8): 1781-1792, 2018 08.
Article en En | MEDLINE | ID: mdl-29720560
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Proteína Supresora de Tumores del Síndrome de Von Hippel-Lindau / Neoplasias Renales / Ácido Mevalónico Límite: Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2018 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Proteína Supresora de Tumores del Síndrome de Von Hippel-Lindau / Neoplasias Renales / Ácido Mevalónico Límite: Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2018 Tipo del documento: Article