Sabellastarte magnifica Carboxypeptidase Inhibitor: The first Kunitz inhibitor simultaneously interacting with carboxypeptidases and serine proteases.

Reytor González, Mey Ling; Alonso-Del-Rivero Antigua, Maday; Hedstrom, Lizbeth; Kuzmic, Petr; Pires, José Ricardo

Reytor González, Mey Ling; Alonso-Del-Rivero Antigua, Maday; Hedstrom, Lizbeth; Kuzmic, Petr; Pires, José Ricardo.

Afiliación

Reytor González ML; Center for Protein Studies, Faculty of Biology, Havana University, 25 St. #455. Vedado, Havana City, 10400, Cuba.
Alonso-Del-Rivero Antigua M; Center for Protein Studies, Faculty of Biology, Havana University, 25 St. #455. Vedado, Havana City, 10400, Cuba. Electronic address: maday@fbio.uh.cu.
Hedstrom L; Bandeis University, Department of Chemistry, 415 South St. MS 009, Waltham, MA, 02454-9110, USA.
Kuzmic P; BioKin Ltd., 15 Main St. Suite 232, Watertown, MA, 02472, USA.
Pires JR; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373 - Bloco E, sala 10, Rio de Janeiro, RJ, 21941-902, Brazil. Electronic address: murari@bioqmed.ufrj.br.

Biochimie ; 150: 37-47, 2018 Jul.

Article en En | MEDLINE | ID: mdl-29730302

Asunto(s)

Carboxipeptidasas/antagonistas & inhibidores; Carboxipeptidasas/metabolismo; Poliquetos/enzimología; Inhibidores de Proteasas/química; Serina Proteasas/metabolismo; Animales; Cinética; Espectroscopía de Resonancia Magnética; Tripsina/química; Tripsina/metabolismo

Palabras clave

BPTI-Kunitz inhibitor; Kinetic assays; Multi-domain inhibitor; Nuclear magnetic resonance; Proteolytic enzymes; Stoichiometry of interaction

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Poliquetos / Inhibidores de Proteasas / Carboxipeptidasas / Serina Proteasas Límite: Animals Idioma: En Revista: Biochimie Año: 2018 Tipo del documento: Article País de afiliación: Cuba

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