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Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma.
Ligtenberg, Maarten A; Pico de Coaña, Yago; Shmushkovich, Taisia; Yoshimoto, Yuya; Truxova, Iva; Yang, Yuan; Betancur-Boissel, Monica; Eliseev, Alexey V; Wolfson, Alexey D; Kiessling, Rolf.
Afiliación
  • Ligtenberg MA; Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm 17176, Sweden.
  • Pico de Coaña Y; Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm 17176, Sweden. Electronic address: yagopico@gmail.com.
  • Shmushkovich T; Advirna LLC, Worcester, MA 01605, USA.
  • Yoshimoto Y; Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm 17176, Sweden; Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi 371-8510, Japan.
  • Truxova I; Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm 17176, Sweden; Charles University, 2(nd) Faculty of Medicine and University Hospital Motol, 150 06 Prague, Czech Republic; Sotio A.S., 170 00 Prague, Czech Republic.
  • Yang Y; Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm 17176, Sweden; Clinical Research Center, Guizhou Medical University Hospital, Guiyang 550025, People's Republic of China.
  • Betancur-Boissel M; Advirna LLC, Worcester, MA 01605, USA.
  • Eliseev AV; RXi Pharmaceuticals, Marlborough, MA 01752, USA.
  • Wolfson AD; Advirna LLC, Worcester, MA 01605, USA.
  • Kiessling R; Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm 17176, Sweden.
Mol Ther ; 26(6): 1482-1493, 2018 06 06.
Article en En | MEDLINE | ID: mdl-29735366
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Receptor de Muerte Celular Programada 1 / Neoplasias Pulmonares / Melanoma Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2018 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Receptor de Muerte Celular Programada 1 / Neoplasias Pulmonares / Melanoma Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2018 Tipo del documento: Article País de afiliación: Suecia