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STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
Skoulidis, Ferdinandos; Goldberg, Michael E; Greenawalt, Danielle M; Hellmann, Matthew D; Awad, Mark M; Gainor, Justin F; Schrock, Alexa B; Hartmaier, Ryan J; Trabucco, Sally E; Gay, Laurie; Ali, Siraj M; Elvin, Julia A; Singal, Gaurav; Ross, Jeffrey S; Fabrizio, David; Szabo, Peter M; Chang, Han; Sasson, Ariella; Srinivasan, Sujaya; Kirov, Stefan; Szustakowski, Joseph; Vitazka, Patrik; Edwards, Robin; Bufill, Jose A; Sharma, Neelesh; Ou, Sai-Hong I; Peled, Nir; Spigel, David R; Rizvi, Hira; Aguilar, Elizabeth Jimenez; Carter, Brett W; Erasmus, Jeremy; Halpenny, Darragh F; Plodkowski, Andrew J; Long, Niamh M; Nishino, Mizuki; Denning, Warren L; Galan-Cobo, Ana; Hamdi, Haifa; Hirz, Taghreed; Tong, Pan; Wang, Jing; Rodriguez-Canales, Jaime; Villalobos, Pamela A; Parra, Edwin R; Kalhor, Neda; Sholl, Lynette M; Sauter, Jennifer L; Jungbluth, Achim A; Mino-Kenudson, Mari.
Afiliación
  • Skoulidis F; Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Goldberg ME; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Greenawalt DM; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Hellmann MD; Druckenmiller Center for Lung Cancer Research and Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Awad MM; Lowe Center for Thoracic Oncology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Gainor JF; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
  • Schrock AB; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Hartmaier RJ; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Trabucco SE; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Gay L; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Ali SM; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Elvin JA; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Singal G; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Ross JS; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Fabrizio D; Foundation Medicine Inc., Cambridge, Massachusetts.
  • Szabo PM; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Chang H; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Sasson A; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Srinivasan S; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Kirov S; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Szustakowski J; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Vitazka P; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Edwards R; Bristol-Myers Squibb Co., Princeton, New Jersey.
  • Bufill JA; Michiana Hematology Oncology, Mishawaka, Indiana.
  • Sharma N; Novartis Institute of Biomedical Research, East Hanover, New Jersey.
  • Ou SI; Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California.
  • Peled N; Thoracic Cancer Unit, Davidoff Cancer Center, Petach Tiqwa, Israel.
  • Spigel DR; Tel Aviv University, Tel Aviv, Israel.
  • Rizvi H; Sarah Cannon Research Institute, Nashville, Tennessee.
  • Aguilar EJ; Druckenmiller Center for Lung Cancer Research and Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Carter BW; Lowe Center for Thoracic Oncology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Erasmus J; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Halpenny DF; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Plodkowski AJ; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Long NM; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Nishino M; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Denning WL; Department of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Galan-Cobo A; Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hamdi H; Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hirz T; Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Tong P; Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Rodriguez-Canales J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Villalobos PA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Parra ER; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Kalhor N; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Sholl LM; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Sauter JL; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.
  • Jungbluth AA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Mino-Kenudson M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Cancer Discov ; 8(7): 822-835, 2018 07.
Article en En | MEDLINE | ID: mdl-29773717
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Proteínas Serina-Treonina Quinasas / Resistencia a Antineoplásicos / Adenocarcinoma del Pulmón / Nivolumab / Neoplasias Pulmonares / Mutación Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Humans / Male / Middle aged Idioma: En Revista: Cancer Discov Año: 2018 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Proteínas Serina-Treonina Quinasas / Resistencia a Antineoplásicos / Adenocarcinoma del Pulmón / Nivolumab / Neoplasias Pulmonares / Mutación Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Humans / Male / Middle aged Idioma: En Revista: Cancer Discov Año: 2018 Tipo del documento: Article