L-carnosine induces apoptosis/cell cycle arrest via suppression of NF-&#954;B/STAT1 pathway in HCT116 colorectal cancer cells.

Lee, Jooyeon; Park, Jeong-Ran; Lee, Hanbyeol; Jang, Soojin; Ryu, Se-Min; Kim, Hyejin; Kim, Donguk; Jang, Aera; Yang, Se-Ran

L-carnosine induces apoptosis/cell cycle arrest via suppression of NF-κB/STAT1 pathway in HCT116 colorectal cancer cells.

Lee, Jooyeon; Park, Jeong-Ran; Lee, Hanbyeol; Jang, Soojin; Ryu, Se-Min; Kim, Hyejin; Kim, Donguk; Jang, Aera; Yang, Se-Ran.

Afiliación

Lee J; Department of Thoracic and Cardiovascular Surgery, Kangwon National University, Chuncheon, 24341, South Korea.
Park JR; Department of Thoracic and Cardiovascular Surgery, Kangwon National University, Chuncheon, 24341, South Korea.
Lee H; Department of Thoracic and Cardiovascular Surgery, Kangwon National University, Chuncheon, 24341, South Korea.
Jang S; Department of Thoracic and Cardiovascular Surgery, Kangwon National University, Chuncheon, 24341, South Korea.
Ryu SM; Department of Thoracic and Cardiovascular Surgery, Kangwon National University, Chuncheon, 24341, South Korea.
Kim H; Department of Animal Products and Food Science, Kangwon National University, Chuncheon, 24341, South Korea.
Kim D; Department of Animal Products and Food Science, Kangwon National University, Chuncheon, 24341, South Korea.
Jang A; Department of Animal Products and Food Science, Kangwon National University, Chuncheon, 24341, South Korea. ajang@kangwon.ac.kr.
Yang SR; Department of Thoracic and Cardiovascular Surgery, Kangwon National University, Chuncheon, 24341, South Korea. seran@kangwon.ac.kr.

In Vitro Cell Dev Biol Anim ; 54(7): 505-512, 2018 Aug.

Article en En | MEDLINE | ID: mdl-29869056

Asunto(s)

Apoptosis/efectos de los fármacos; Carnosina/farmacología; Puntos de Control del Ciclo Celular/efectos de los fármacos; Neoplasias Colorrectales/metabolismo; Neoplasias Colorrectales/patología; FN-kappa B/metabolismo; Factor de Transcripción STAT1/metabolismo; Proliferación Celular/efectos de los fármacos; Inhibidor p21 de las Quinasas Dependientes de la Ciclina/metabolismo; Fase G1/efectos de los fármacos; Células HCT116; Humanos; Modelos Biológicos; Fosforilación/efectos de los fármacos; Fase de Descanso del Ciclo Celular/efectos de los fármacos; Proteína p53 Supresora de Tumor/metabolismo

Palabras clave

Apoptosis; Cell cycle arrest; Colorectal cancer; L-carnosine; NF-κB p65; STAT1

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carnosina / Neoplasias Colorrectales / FN-kappa B / Apoptosis / Factor de Transcripción STAT1 / Puntos de Control del Ciclo Celular Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: In Vitro Cell Dev Biol Anim Asunto de la revista: BIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Corea del Sur

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