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CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.
Ale-Agha, Niloofar; Goy, Christine; Jakobs, Philipp; Spyridopoulos, Ioakim; Gonnissen, Stefanie; Dyballa-Rukes, Nadine; Aufenvenne, Karin; von Ameln, Florian; Zurek, Mark; Spannbrucker, Tim; Eckermann, Olaf; Jakob, Sascha; Gorressen, Simone; Abrams, Marcel; Grandoch, Maria; Fischer, Jens W; Köhrer, Karl; Deenen, René; Unfried, Klaus; Altschmied, Joachim; Haendeler, Judith.
Afiliación
  • Ale-Agha N; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Goy C; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Jakobs P; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Spyridopoulos I; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Gonnissen S; Core Unit Biosafety Level 2 Laboratory, IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Dyballa-Rukes N; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Aufenvenne K; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • von Ameln F; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Zurek M; Core Unit Biosafety Level 2 Laboratory, IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Spannbrucker T; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Eckermann O; Environmentally-induced Skin and Lung Aging, IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Jakob S; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Gorressen S; Heisenberg-group-Environmentally-induced Cardiovascular Degeneration, Medical Faculty, HHU Duesseldorf and IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Abrams M; Institute for Pharmacology and Clinical Pharmacology, Medical Faculty, HHU Duesseldorf, Duesseldorf, Germany.
  • Grandoch M; Institute for Pharmacology and Clinical Pharmacology, Medical Faculty, HHU Duesseldorf, Duesseldorf, Germany.
  • Fischer JW; Institute for Pharmacology and Clinical Pharmacology, Medical Faculty, HHU Duesseldorf, Duesseldorf, Germany.
  • Köhrer K; Institute for Pharmacology and Clinical Pharmacology, Medical Faculty, HHU Duesseldorf, Duesseldorf, Germany.
  • Deenen R; Biological and Medical Research Center (BMFZ), HHU, Duesseldorf, Germany.
  • Unfried K; Biological and Medical Research Center (BMFZ), HHU, Duesseldorf, Germany.
  • Altschmied J; Environmentally-induced Skin and Lung Aging, IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
  • Haendeler J; Core Unit Biosafety Level 2 Laboratory, IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
PLoS Biol ; 16(6): e2004408, 2018 06.
Article en En | MEDLINE | ID: mdl-29927970
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cafeína / Cardiotónicos / Miocitos Cardíacos / Inhibidor p27 de las Quinasas Dependientes de la Ciclina / Mitocondrias / Infarto del Miocardio Límite: Animals / Humans Idioma: En Revista: PLoS Biol Asunto de la revista: BIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cafeína / Cardiotónicos / Miocitos Cardíacos / Inhibidor p27 de las Quinasas Dependientes de la Ciclina / Mitocondrias / Infarto del Miocardio Límite: Animals / Humans Idioma: En Revista: PLoS Biol Asunto de la revista: BIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Alemania