Controlled Release of 5-Fluorouracil from Alginate Beads Encapsulated in 3D Printed pH-Responsive Solid Dosage Forms.

Gioumouxouzis, Christos I; Chatzitaki, Aikaterini-Theodora; Karavasili, Christina; Katsamenis, Orestis L; Tzetzis, Dimitrios; Mystiridou, Emmanouela; Bouropoulos, Nikolaos; Fatouros, Dimitrios G

Gioumouxouzis, Christos I; Chatzitaki, Aikaterini-Theodora; Karavasili, Christina; Katsamenis, Orestis L; Tzetzis, Dimitrios; Mystiridou, Emmanouela; Bouropoulos, Nikolaos; Fatouros, Dimitrios G.

Afiliación

Gioumouxouzis CI; Laboratory of Pharmaceutical Technology, School of Pharmacy, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece.
Chatzitaki AT; Laboratory of Pharmaceutical Technology, School of Pharmacy, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece.
Karavasili C; Laboratory of Pharmaceutical Technology, School of Pharmacy, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece.
Katsamenis OL; µ-VIS X-Ray Imaging Centre, Faculty of Engineering and the Environment, University of Southampton, Southampton, SO17 1BJ, UK.
Tzetzis D; School of Science and Technology, International Hellenic University, 14km Thessaloniki - N. Moudania, GR57001, Thermi, Greece.
Mystiridou E; Foundation for Research and Technology Hellas, Institute of Chemical Engineering and High Temperature Chemical Processes, Patras, Greece.
Bouropoulos N; Department of Materials Science, University of Patras, 26504, Rio, Patras, Greece.
Fatouros DG; Foundation for Research and Technology Hellas, Institute of Chemical Engineering and High Temperature Chemical Processes, Patras, Greece.

AAPS PharmSciTech ; 19(8): 3362-3375, 2018 Nov.

Article en En | MEDLINE | ID: mdl-29948989

Asunto(s)

Ácido Algínico/química; Fluorouracilo/química; Impresión Tridimensional; Ácido Algínico/farmacocinética; Rastreo Diferencial de Calorimetría/métodos; Preparaciones de Acción Retardada/química; Preparaciones de Acción Retardada/farmacocinética; Formas de Dosificación; Liberación de Fármacos; Excipientes/química; Excipientes/farmacocinética; Fluorouracilo/farmacocinética; Concentración de Iones de Hidrógeno; Comprimidos/química; Tecnología Farmacéutica/métodos; Difracción de Rayos X/métodos

Palabras clave

5-FU; alginate beads; colonic delivery; microfocus computed tomography; three-dimensional printing

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Impresión Tridimensional / Fluorouracilo / Ácido Algínico Idioma: En Revista: AAPS PharmSciTech Asunto de la revista: FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Grecia

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