Identification of an enhancer region within the TP63/LEPREL1 locus containing genetic variants associated with bladder cancer risk.

Dudek, Aleksandra M; Vermeulen, Sita H; Kolev, Dimitar; Grotenhuis, Anne J; Kiemeney, Lambertus A L M; Verhaegh, Gerald W

Dudek, Aleksandra M; Vermeulen, Sita H; Kolev, Dimitar; Grotenhuis, Anne J; Kiemeney, Lambertus A L M; Verhaegh, Gerald W.

Afiliación

Dudek AM; Department of Urology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.
Vermeulen SH; Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Kolev D; Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Grotenhuis AJ; Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Kiemeney LALM; Department of Urology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein Zuid 28, 6525 GA, Nijmegen, The Netherlands.
Verhaegh GW; Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

Cell Oncol (Dordr) ; 41(5): 555-568, 2018 Oct.

Article en En | MEDLINE | ID: mdl-29956121

Asunto(s)

Variación Genética/genética; Procolágeno-Prolina Dioxigenasa/genética; Factores de Transcripción/genética; Proteínas Supresoras de Tumor/genética; Neoplasias de la Vejiga Urinaria/genética; Línea Celular; Supervivencia Celular/genética; Supervivencia Celular/fisiología; Predisposición Genética a la Enfermedad/genética; Estudio de Asociación del Genoma Completo; Genotipo; Humanos; Polimorfismo de Nucleótido Simple/genética

Palabras clave

Bladder cancer; Enhancer; Genome-wide association study; LEPREL1 gene; Single-nucleotide polymorphism; TP63 gene

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Variación Genética / Neoplasias de la Vejiga Urinaria / Procolágeno-Prolina Dioxigenasa / Proteínas Supresoras de Tumor Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cell Oncol (Dordr) Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos

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